Butanoic acid, 2,2,2-trifluoroethyl ester

Butanoic acid, 2,2,2-trifluoroethyl ester - Names and Identifiers

Name	2,2,2-trifluoroethyl butyrate
Synonyms	Butyric acid, TFE 2,2,2-TRIFLUOROETHYL BUTYRATE 2,2,2-trifluoroethyl butyrate 2,2,2-TRIFLUOROETHYL N-BUTYRATE Butyric Acid 2,2,2-Trifluoroethyl Ester Butanoic acid, 2,2,2-trifluoroethyl ester N-BUTYRIC ACID 2,2,2-TRIFLUOROETHYL ESTER
CAS	371-27-7
InChI	InChI=1/C6H9F3O2/c1-2-3-5(10)11-4-6(7,8)9/h2-4H2,1H3

Butanoic acid, 2,2,2-trifluoroethyl ester - Physico-chemical Properties

Molecular Formula	C6H9F3O2
Molar Mass	170.13
Density	1.127g/mLat 25°C(lit.)
Boling Point	113°C747mm Hg(lit.)
Flash Point	75°F
Vapor Presure	32.4mmHg at 25°C
Specific Gravity	1.127
BRN	1769212
Storage Condition	Room Temprature
Refractive Index	n20/D 1.347(lit.)
MDL	MFCD00077609

Butanoic acid, 2,2,2-trifluoroethyl ester - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	UN 3272 3/PG 2
WGK Germany	3
FLUKA BRAND F CODES	10-21
HS Code	29156000
Hazard Note	Irritant
Hazard Class	3.2
Packing Group	III

Butanoic acid, 2,2,2-trifluoroethyl ester - Introduction

2,2,2-trifluoroethyl butyrate is an organic compound with the chemical formula C6H9F3O2. The following is a description of the nature, use, preparation and safety information of 2,2,2-trifluoroethyl butyrate:

Nature:
-Appearance: colorless liquid
-Odor: Has a special odor
-Boiling point: about 105-106°C
-Melting point: approx. -60°C
-Density: Approximately 1.24 g/mL
-Solubility: Soluble in ethanol, ether and chloroform, insoluble in water

Use:
- 2,2,2-trifluoroethyl butyrate is often used as a solvent in organic synthesis, especially for compounds with high polarity.
-It can also be used as a solvent in the pharmaceutical intermediate, fragrance and coating industries.

Preparation Method:
2,2,2-trifluoroethyl butyrate can be prepared in a variety of ways, the commonly used methods include:
1. Butyric acid reacts with 2,2, 2-trifluoroethanol to generate 2,2,2-trifluoroethyl butyrate.
2. Through transesterification reaction, butyric acid and ethyl 2,2, 2-trifluoroacetate are used to react to generate 2,2,2-trifluoroethyl butyrate.

Safety Information:
- 2,2,2-trifluoroethyl butyrate is irritating and may have an irritating effect on the skin and eyes. Avoid direct contact with skin and eyes during use.
-When using or storing, care should be taken to avoid fire and high temperature. It is a flammable liquid and should be stored in a closed container, away from fire and high temperature areas.
-If there is an accidental leak or contact, rinse immediately with plenty of running water and seek medical help.

Please note that this introduction is for reference only. The specific use and operation should also follow the relevant chemical operation specifications and pay attention to safety.

Last Update：2024-04-09 15:17:57